59892-37-4

59892-37-4 structure

Name: 1-(2,3,5-Tribenzoyl--D-ribofuranosyl)-5-nitropyridine-2(1H)-one
Chemical Name: 1-(2,3,5-tri-O-benzoyl-β-D-ribofuranosyl)-5-nitropyridin-2-one
CAS Number: 59892-37-4
Molecular Formula: C₃₁H₂₄N₂O₁₀
Molecular Weight: 584.53
Catalog: Signaling Pathways Cell Cycle/DNA Damage Nucleoside Antimetabolite/Analog
Create Date: 2018-03-06 07:51:51
Modify Date: 2024-01-08 18:07:35
5-Nitro-1-(2,3,5-tri-O-benzoyl-β-D-ribofuranosyl)-2(1H)-pyridinone is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Name	1-(2,3,5-tri-O-benzoyl-β-D-ribofuranosyl)-5-nitropyridin-2-one
Synonyms	1-(2,3,5-tri-O-benzoyl-β-D-ribofuranosyl)-5-nitropyridine-2(1H)-one 5-nitro-1-(2,3,5-tri-O-benzoyl-β-D-ribofuranosyl)-2-pyridone

Description	5-Nitro-1-(2,3,5-tri-O-benzoyl-β-D-ribofuranosyl)-2(1H)-pyridinone is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog
References	[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.