208645-74-3

208645-74-3 structure

Name: H-Gly-Gly-AMC hydrochloride salt
Chemical Name: Gly-Gly-MCA
CAS Number: 208645-74-3
Molecular Formula: C₁₄H₁₅N₃O₄
Molecular Weight: 289.28700
Catalog: Research Areas Others
Create Date: 2018-12-11 19:44:28
Modify Date: 2024-01-09 15:22:59
Gly-Gly-AMC is a fluorogenic peptide substrate. Gly-Gly-AMC can be used to assess bacterial protease activity of P. aeruginosa and S. aureus[1][2].

Name	Gly-Gly-MCA
Synonyms	gg-mca H-Gly-Gly-AMC Glycyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)glycinamide

Description	Gly-Gly-AMC is a fluorogenic peptide substrate. Gly-Gly-AMC can be used to assess bacterial protease activity of P. aeruginosa and S. aureus[1][2].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
In Vitro	Gly-Gly-AMC can be hydrolyzed at very low levels by SW480 and T47D cell extracts[1]. Gly-Gly-AMC can be used to assess bacterial protease activity of P. aeruginosa and S. aureus[2].
References	[1]. Berger Y, et al. Determination of intracellular prolyl/glycyl proteases in intact living human cells and protoporphyrin IX production as a reporter system. Chem Biol. 2005 Aug;12(8):867-72. [2]. Wildeboer D, et al. Characterization of bacterial proteases with a panel of fluorescent peptide substrates. Anal Biochem. 2009 Jan 15;384(2):321-8.