Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 5-Methoxy-quinazoline-2,4-diamine
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

27018-21-9

27018-21-9 structure

Name: 5-Methoxyquinazoline-2,4-diamine
Chemical Name: 5-Methoxy-quinazoline-2,4-diamine
CAS Number: 27018-21-9
Molecular Formula: C₉H₁₀N₄O
Molecular Weight: 190.20200
Create Date: 2018-12-26 20:44:59
Modify Date: 2024-01-05 16:53:44

Name	5-Methoxy-quinazoline-2,4-diamine
Synonyms	5-methoxyquinazoline-2,4-diamine 2,4-diamino-5-methoxyquinazoline 2,4-Quinazolinediamine,5-methoxy 5-Methoxy-2,4-chinazolindiamin 5-Methoxy-2,4-diaminoquinazoline

Density	1.372g/cm3
Boiling Point	484.8ºC at 760mmHg
Molecular Formula	C₉H₁₀N₄O
Molecular Weight	190.20200
Flash Point	247ºC
Exact Mass	190.08500
PSA	87.05000
LogP	1.96520
Vapour Pressure	1.49E-09mmHg at 25°C
Index of Refraction	1.732

CHEMICAL IDENTIFICATION

RTECS NUMBER :: VA1367800

CHEMICAL NAME :: 2,4-Quinazolinediamine, 5-methoxy-

CAS REGISTRY NUMBER :: 27018-21-9

BEILSTEIN REFERENCE NO. :: 0746085

LAST UPDATED :: 199612

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C9-H10-N4-O

MOLECULAR WEIGHT :: 190.23

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 33,434,1990

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 137 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 33,434,1990

HS Code	2933990090

593-85-1

67-56-1

1897-52-5

~71%

27018-21-9

Literature: Shanghai Institute Materia Medica, Chinese Academy Of Sciences; ZUO, Jianping; HU, Youhong; TANG, Wei; CHAO, Bo; TONG, Xiankun; LI, Dewen; JI, Feihong; HE, Peilan Patent: EP2649999 A1, 2013 ; Location in patent: Paragraph 0023 ;

124-46-9

94088-46-7

~92%

27018-21-9

Literature: Hynes, John B.; Pathak, Alpana; Panos, Constantina H.; Okeke, Claudia C. Journal of Heterocyclic Chemistry, 1988 , vol. 25, p. 1173 - 1177

1591-37-3

593-85-1

~40%

27018-21-9

Literature: Thurmond, John; Butchbach, Matthew E. R.; Palomo, Marty; Pease, Brian; Rao, Munagala; Bedell, Louis; Keyvan, Monica; Pai, Grace; Mishra, Rama; Haraldsson, Magnus; Andresson, Thorkell; Bragason, Gisli; Thosteinsdottir, Margret; Bjornsson, Jon Mar; Coovert, Daniel D.; Burghes, Arthur H. M.; Gurney, Mark E.; Singh, Jasbir Journal of Medicinal Chemistry, 2008 , vol. 51, # 3 p. 449 - 469

1897-52-5

27018-21-9

Literature: SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES; Zuo, Jianping; Hu, Youhong; Tang, Wei; Chao, Bo; Tong, Xiankun; Li, Dewen; Ji, Feihong; He, Peilan Patent: US2013/261139 A1, 2013 ;

1591-37-3

29671-92-9

27018-21-9

Literature: Nelson; Rosowsky Antimicrobial Agents and Chemotherapy, 2001 , vol. 45, # 12 p. 3293 - 3303

HS Code	2933990090
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

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