448954-98-1
448954-98-1 structure
- Name: NH2-O-C5-COOH hydrobromide
- Chemical Name: 6-aminooxyhexanoic acid,hydrobromide
- CAS Number: 448954-98-1
- Molecular Formula: C6H14BrNO3
- Molecular Weight: 228.08400
- Catalog: Signaling Pathways PROTAC PROTAC Linker
- Create Date: 2018-06-23 12:53:38
- Modify Date: 2024-01-05 22:37:34
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NH2-O-C5-COOH (hydrobromide) is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].
| Name | 6-aminooxyhexanoic acid,hydrobromide |
|---|---|
| Synonyms |
6-Aminooxy-hexanoic acid hydrobromide
6-Aminooxy-hexanoic acid Hexanoicacid,6-(aminooxy)-,hydrobromide (1:1) |
| Description | NH2-O-C5-COOH (hydrobromide) is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
|---|---|
| Related Catalog | |
| Target |
Alkyl-Chain |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| References |
| Boiling Point | 349.5ºC at 760 mmHg |
|---|---|
| Molecular Formula | C6H14BrNO3 |
| Molecular Weight | 228.08400 |
| Flash Point | 165.2ºC |
| Exact Mass | 227.01600 |
| PSA | 72.55000 |
| LogP | 2.18010 |