126502-12-3

126502-12-3 structure

Name: 2’-Fluoro-2’-deoxy-N6-methylarabinoadenosine
Chemical Name: N6-methyl-9-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)adenine
CAS Number: 126502-12-3
Molecular Formula: C₁₁H₁₄FN₅O₃
Molecular Weight: 283.26
Catalog: Signaling Pathways Cell Cycle/DNA Damage Nucleoside Antimetabolite/Analog
Create Date: 2018-06-14 19:56:51
Modify Date: 2024-01-24 16:45:42
2’-Fluoro-2’-deoxy-N6-methylarabinoadenosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Name	N6-methyl-9-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)adenine
Synonyms	(2r,3r,4s,5r)-4-fluoro-2-(hydroxymethyl)-5-(6-(methylamino)-9h-purin-9-yl)tetrahydrofuran-3-ol

Description	2’-Fluoro-2’-deoxy-N6-methylarabinoadenosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog	Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog Research Areas >> Others
References	[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.