640725-74-2

640725-74-2 structure

Name: 2-Amino-6-chloro-9-(2-C-Methyl-β-D-ribofuranosyl)-9H-purine
Chemical Name: 2-amino-6-chloro-9-(2-C-methyl-β-D-ribofuranosyl)purine
CAS Number: 640725-74-2
Molecular Formula: C₁₁H₁₄ClN₅O₄
Molecular Weight: 315.71
Catalog: Signaling Pathways Cell Cycle/DNA Damage Nucleoside Antimetabolite/Analog
Create Date: 2018-01-02 15:11:38
Modify Date: 2024-01-20 00:44:31
2-Amino -6-chloro-9-(2-β-C-methyl-β-D-ribofuranosyl)-9H-purine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Name	2-amino-6-chloro-9-(2-C-methyl-β-D-ribofuranosyl)purine
Synonyms	2-(2-amino-6-chloro-9H-purin-9-yl)-5-(hydroxymethyl)-3-methyl tetrahydrofuran-3,4-diol 2-amino-6-chloro-9-(2-C-methyl-β-D-ribofuranosyl)-9H-purine

Description	2-Amino -6-chloro-9-(2-β-C-methyl-β-D-ribofuranosyl)-9H-purine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog	Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog Research Areas >> Others
References	[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.