19056-75-8

19056-75-8 structure

Name: 3,7,2',4'-Tetramethoxy-5-hydroxyflavone
Chemical Name: 2-(2,4-dimethoxyphenyl)-5-hydroxy-3,7-dimethoxy-4H-chromen-4-one
CAS Number: 19056-75-8
Molecular Formula: C₁₉H₁₈O₇
Molecular Weight: 358.34200
Catalog: Signaling Pathways Membrane Transporter/Ion Channel BCRP
Create Date: 2018-03-01 16:44:05
Modify Date: 2024-01-06 12:33:35
BCRP/ABCG2-IN-1 is the inhibitor of breast cancer resistance protein (BCRP/ABCG2), with IC50 of 5.98 μM, that can be used in multidrug resistance of breast cancer[1].

Name	2-(2,4-dimethoxyphenyl)-5-hydroxy-3,7-dimethoxy-4H-chromen-4-one
Synonyms	2',3,4',7-tetramethoxy-5-hydroxyflavone 5-hydroxy-3,7,2',4'-tetramethoxyflavone 2-(2,4-dimethoxy-phenyl)-5-hydroxy-3,7-dimethoxy-chromen-4-one 2-(2,4-Dimethoxy-phenyl)-5-hydroxy-3,7-dimethoxy-chromen-4-on

Description	BCRP/ABCG2-IN-1 is the inhibitor of breast cancer resistance protein (BCRP/ABCG2), with IC50 of 5.98 μM, that can be used in multidrug resistance of breast cancer[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Membrane Transporter/Ion Channel >> BCRP
References	[1]. Kapil Juvale, et al. Synthesis and biological evaluation of flavones and benzoflavones as inhibitors of BCRP/ABCG2. Eur J Med Chem. 2013 Sep:67:115-26.