898157-46-5
898157-46-5 structure
- Name: 1-Oxa-8-azaspiro[4,5]decane-8-carboxylic acid,3-bromo-,1,1-dimethylethylester
- Chemical Name: 1-Oxa-8-azaspiro[4,5]decane-8-carboxylic acid,3-bromo-,1,1-dimethylethylester
- CAS Number: 898157-46-5
- Molecular Formula: C13H22BrNO3
- Molecular Weight: 320.223
- Create Date: 2018-12-22 08:04:43
- Modify Date: 2024-04-05 11:05:02
| Name | 1-Oxa-8-azaspiro[4,5]decane-8-carboxylic acid,3-bromo-,1,1-dimethylethylester |
|---|---|
| Synonyms |
2-Methyl-2-propanyl 3-bromo-1-oxa-8-azaspiro[4.5]decane-8-carboxylate
1-Oxa-8-azaspiro[4.5]decane-8-carboxylic acid, 3-bromo-, 1,1-dimethylethyl ester tert-butyl (3R,5S)-6-amino-3,5-O-isopropylidene-3,5-dihydroxyhexanoate (4R-Cis)-1,1-Dimethylethyl-6-Aminomethyl-2,2-Dimethyl-1,3-Dioxane-4-Acetate tert-Butyl-3-brom-1-oxa-8-azaspiro[4.5]decan-8-carboxylat tert-butyl (3RS)-3-bromo-1-oxa-8-azaspiro[4.5]decane-8-carboxylate Tert-butyl[(4R,6R)-6-(2-aminoethyl)-2,2-dimethyl-1,3-dioxan-4-yl]acetate |
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Boiling Point | 381.7±42.0 °C at 760 mmHg |
| Molecular Formula | C13H22BrNO3 |
| Molecular Weight | 320.223 |
| Flash Point | 184.6±27.9 °C |
| Exact Mass | 319.078308 |
| PSA | 38.77000 |
| LogP | 1.82 |
| Vapour Pressure | 0.0±0.9 mmHg at 25°C |
| Index of Refraction | 1.532 |
|
~42%
898157-46-5 |
| Literature: PFIZER INC.; LONG, Scott Allen; MEYERS, Marvin Jay; PELC, Matthew James; SCHWEITZER, Barbara Ann; THORARENSEN, Atli; WANG, Lijuan Jane Patent: WO2010/58318 A1, 2010 ; Location in patent: Page/Page column 26 ; WO 2010/058318 A1 |
|
~%
898157-46-5 |
| Literature: Meyers, Marvin J.; Long, Scott A.; Pelc, Matthew J.; Wang, Jane L.; Bowen, Scott J.; Schweitzer, Barbara A.; Wilcox, Mark V.; McDonald, Joseph; Smith, Sarah E.; Foltin, Susan; Rumsey, Jeanne; Yang, Young-Sun; Walker, Mark C.; Kamtekar, Satwik; Beidler, David; Thorarensen, Atli Bioorganic and Medicinal Chemistry Letters, 2011 , vol. 21, # 21 p. 6545 - 6553 |
| Precursor 2 | |
|---|---|
| DownStream 0 | |