464190-91-8

464190-91-8 structure

Name: Azido-PEG1-amine
Chemical Name: 2-(2-azidoethoxy)ethanamine
CAS Number: 464190-91-8
Molecular Formula: C₄H₁₀N₄O
Molecular Weight: 130.14800
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2018-06-17 17:56:23
Modify Date: 2024-01-15 08:26:05
Azido-PEG1-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	2-(2-azidoethoxy)ethanamine
Synonyms	N3-PEG1-CH2CH2NH2 N3-PEG2-NH2

Description	Azido-PEG1-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562