1246535-95-4

1246535-95-4 structure

Name: Desmethyl VS-5584
Chemical Name: 5-(9-isopropyl-2-morpholino-9H-purin-6-yl)pyrimidin-2-amine
CAS Number: 1246535-95-4
Molecular Formula: C₁₆H₂₀N₈O
Molecular Weight: 340.383
Catalog: Signaling Pathways PI3K/Akt/mTOR mTOR
Create Date: 2018-12-17 12:21:58
Modify Date: 2024-01-19 12:00:56
Desmethyl-VS-5584 is a dimethyl analog of VS-5584 which is an potent and selective mTOR/PI3K dual inhibitor with pyrido [2,3-d] pyrimidine structure[1].

Name	5-(9-isopropyl-2-morpholino-9H-purin-6-yl)pyrimidin-2-amine
Synonyms	2-Pyrimidinamine, 5-[9-(1-methylethyl)-2-(4-morpholinyl)-9H-purin-6-yl]- 5-[9-Isopropyl-2-(4-morpholinyl)-9H-purin-6-yl]-2-pyrimidinamine 5-(9-isopropyl-2-morpholin-4-yl-9H-purin-6-yl)-pyrimidin-2-ylamine 5-(9-isopropyl-2-morpholin-4-yl-9H-purin-6-yl)pyrimidin-2-ylamine Desmethyl VS-5584

Description	Desmethyl-VS-5584 is a dimethyl analog of VS-5584 which is an potent and selective mTOR/PI3K dual inhibitor with pyrido [2,3-d] pyrimidine structure[1].
Related Catalog	Signaling Pathways >> PI3K/Akt/mTOR >> mTOR Research Areas >> Cancer Signaling Pathways >> PI3K/Akt/mTOR >> PI3K
References	[1]. Hart S, Novotny-Diermayr V, Goh KC, et al. VS-5584, a novel and highly selective PI3K/mTOR kinase inhibitor for the treatment of cancer. Mol Cancer Ther. 2013;12(2):151-161.