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1246535-95-4

1246535-95-4 structure
1246535-95-4 structure
  • Name: Desmethyl VS-5584
  • Chemical Name: 5-(9-isopropyl-2-morpholino-9H-purin-6-yl)pyrimidin-2-amine
  • CAS Number: 1246535-95-4
  • Molecular Formula: C16H20N8O
  • Molecular Weight: 340.383
  • Catalog: Signaling Pathways PI3K/Akt/mTOR mTOR
  • Create Date: 2018-12-17 12:21:58
  • Modify Date: 2024-01-19 12:00:56
  • Desmethyl-VS-5584 is a dimethyl analog of VS-5584 which is an potent and selective mTOR/PI3K dual inhibitor with pyrido [2,3-d] pyrimidine structure[1].

Name 5-(9-isopropyl-2-morpholino-9H-purin-6-yl)pyrimidin-2-amine
Synonyms 2-Pyrimidinamine, 5-[9-(1-methylethyl)-2-(4-morpholinyl)-9H-purin-6-yl]-
5-[9-Isopropyl-2-(4-morpholinyl)-9H-purin-6-yl]-2-pyrimidinamine
5-(9-isopropyl-2-morpholin-4-yl-9H-purin-6-yl)-pyrimidin-2-ylamine
5-(9-isopropyl-2-morpholin-4-yl-9H-purin-6-yl)pyrimidin-2-ylamine
Desmethyl VS-5584
Description Desmethyl-VS-5584 is a dimethyl analog of VS-5584 which is an potent and selective mTOR/PI3K dual inhibitor with pyrido [2,3-d] pyrimidine structure[1].
Related Catalog
References

[1]. Hart S, Novotny-Diermayr V, Goh KC, et al. VS-5584, a novel and highly selective PI3K/mTOR kinase inhibitor for the treatment of cancer. Mol Cancer Ther. 2013;12(2):151-161.

Density 1.5±0.1 g/cm3
Boiling Point 669.3±65.0 °C at 760 mmHg
Molecular Formula C16H20N8O
Molecular Weight 340.383
Flash Point 358.6±34.3 °C
Exact Mass 340.175995
PSA 107.87000
LogP -0.67
Vapour Pressure 0.0±2.0 mmHg at 25°C
Index of Refraction 1.766
Storage condition -20℃