669556-83-6

669556-83-6 structure

Name: THP-PEG9-OH
Chemical Name: 2-{2-[2-(2-{2-[2-(2-{2-[2-(Tetrahydro-pyran-2-yloxy)-ethoxy]-ethoxy}-ethoxy)-ethoxy]-ethoxy}-ethoxy)-ethoxy]-ethoxy}-ethanol
CAS Number: 669556-83-6
Molecular Formula: C₂₃H₄₆O₁₁
Molecular Weight: 498.60500
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2018-05-14 13:21:17
Modify Date: 2024-01-09 12:59:15
THP-PEG9-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	2-{2-[2-(2-{2-[2-(2-{2-[2-(Tetrahydro-pyran-2-yloxy)-ethoxy]-ethoxy}-ethoxy)-ethoxy]-ethoxy}-ethoxy)-ethoxy]-ethoxy}-ethanol
Synonyms	THP-PEG9-OH

Description	THP-PEG9-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562