117707-51-4

117707-51-4 structure

Name: ENS-163 phosphate
Chemical Name: (+)-(3R-cis)-3-ethyl-4,5-dihydro-4-<(1-methyl-1H-imidazol-5-yl)methyl>-2(3H)-thiophenone dihydrogen phosphate
CAS Number: 117707-51-4
Molecular Formula: C₁₁H₁₉N₂O₅PS
Molecular Weight: 322.31800
Catalog: Signaling Pathways GPCR/G Protein mAChR
Create Date: 2018-06-07 19:39:11
Modify Date: 2025-08-22 10:36:51
ENS-163 phosphate is a selective muscarinic M1 receptor agonist.

Name	(+)-(3R-cis)-3-ethyl-4,5-dihydro-4-<(1-methyl-1H-imidazol-5-yl)methyl>-2(3H)-thiophenone dihydrogen phosphate
Synonyms	(3S,4R)-3-Ethyl-4-(3-methyl-3H-imidazol-4-ylmethyl)-dihydro-thiophen-2-one compound with phosphoric acid (+)-(3R-cis)-3-ethyl-4,5-dihydro-4-[(1-methyl-1H-imidazol-5-yl)methyl]-2(3H)-thiophenone dihydrogen phosphate ENS-163 phosphate

Description	ENS-163 phosphate is a selective muscarinic M1 receptor agonist.
Related Catalog	Signaling Pathways >> GPCR/G Protein >> mAChR Signaling Pathways >> Neuronal Signaling >> mAChR Research Areas >> Neurological Disease
Target	muscarinic M1 receptor[1]
In Vivo	ENS-163 is a selective muscarinic M1 agonist, on long-term potentiation (LTP) is studied in a rat hippocampal slice preparation. ENS-163 facilitates the induction of long-term potentiation in rat hippocampal slices[1].
References	[1]. Boddeke EW, et al. SDZ ENS 163, a selective muscarinic M1 receptor agonist, facilitates the induction of long-term potentiation in rat hippocampal slices. Eur J Pharmacol. 1992 Nov 3;222(1):21-5.