142546-16-5

142546-16-5 structure

Name: 1-oxomiltirone
Chemical Name: 1-oxomiltirone
CAS Number: 142546-16-5
Molecular Formula: C₁₉H₂₀O₃
Molecular Weight: 296.36000
Catalog: Research Areas Others
Create Date: 2018-06-13 10:01:59
Modify Date: 2024-04-05 11:44:25
2-Isopropyl-8,8-dimethyl-7,8-dihydrophenanthrene-3,4,5(6H)-trione is a C20 -norabietane diterpenoid with anti-inflammatory activity. 2-Isopropyl-8,8-dimethyl-7,8-dihydrophenanthrene-3,4,5(6H)-trione can be isolated from sage leaves[1].

Name	1-oxomiltirone
Synonyms	2-Isopropyl-8,8-dimethyl-7,8-dihydro-6H-phenanthrene-3,4,5-trione

Description	2-Isopropyl-8,8-dimethyl-7,8-dihydrophenanthrene-3,4,5(6H)-trione is a C20 -norabietane diterpenoid with anti-inflammatory activity. 2-Isopropyl-8,8-dimethyl-7,8-dihydrophenanthrene-3,4,5(6H)-trione can be isolated from sage leaves[1].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
In Vitro	2-Isopropyl-8,8-dimethyl-7,8-dihydrophenanthrene-3,4,5(6H)-trione（compound 12）对 RAW264.7 细胞中 LPS 刺激的 NO 产生具有抑制作用，IC 50 值为 5.86 μg/mL[1]。
References	[1]. Lingnan Li, et al. Anti-inflammatory norabietane diterpenoids from the leaves of Salvia officinalis L. Journal of Functional Foods 54 (2019) 154-163.