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  • DC Chemicals Limited
  • China
  • Product Name: Exo1
  • Price: $550.0/100mg $950.0/250mg $1800.0/1g
  • Purity: 98.0%
  • Stocking Period: 3 Day
  • Contact: Tony Cao

75541-83-2

75541-83-2 structure
75541-83-2 structure
  • Name: Exo1
  • Chemical Name: methyl 2-[(4-fluorobenzoyl)amino]benzoate
  • CAS Number: 75541-83-2
  • Molecular Formula: C15H12FNO3
  • Molecular Weight: 273.25900
  • Catalog: Research Areas Others
  • Create Date: 2016-02-19 15:25:52
  • Modify Date: 2024-01-05 19:13:46
  • Exo1 is a chemical inhibitor of the exocytic pathway.

Name methyl 2-[(4-fluorobenzoyl)amino]benzoate
Synonyms 2-(4-Fluorobenzoylamino)benzoic acid methyl ester,2-(4-Fluorobenzoylamino)methylbenzoate
2-(4-FLUOROBENZOYLAMINO)BENZOIC ACID METHYL ESTER
2-(4-Fluoro-benzoylami
4-FLUORO-BZ-2-ABZ-OME
EOX 1
2-(2-METHOXY-BENZYL)-SUCCINIC ACID.
EXO1
EXOCYTIC INHIBITOR 1
2-(4-FLUOROBENZOYLAMINO)METHYLBENZOATE
Exo1,Exocytic Inhibitor 1,2-(4-Fluoro-benzoylaMino)-benzoic acid Methyl ester
Description Exo1 is a chemical inhibitor of the exocytic pathway.
Related Catalog
In Vitro Exo1 is a modifier of Golgi ARF1 GTPase activity. Because Exo1 affects a subset of the membrane events that are blocked by BFA, but seems to have a different protein target (and presumably has different side effects), it provides an independent means to interfere with Golgi activity. Exo1 Disrupts Vesicular Traffic from the ER to the Golgi apparatus by disrupting Golgi structures. Exo1 inhibits exocytosis with an IC50 of ~20 μM. Exo1 prevents acquisition of endoglycosidase H resistance by newly synthesized proteins such as VSVGts-GFP, transferrin, and MHC class I[1].
References

[1]. Feng Y, et al. Exo1: a new chemical inhibitor of the exocytic pathway. Proc Natl Acad Sci U S A. 2003 May 27;100(11):6469-74.

Density 1.298 g/cm3
Boiling Point 333.9ºC at 760 mmHg
Molecular Formula C15H12FNO3
Molecular Weight 273.25900
Flash Point 155.8ºC
Exact Mass 273.08000
PSA 55.40000
LogP 2.93760
Storage condition 2-8℃
Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADR NONH for all modes of transport