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119824-66-7

119824-66-7 structure
119824-66-7 structure
  • Name: N-(2-Phenoxyacetyl)guanosine
  • Chemical Name: Gua(pac)
  • CAS Number: 119824-66-7
  • Molecular Formula: C18H19N5O7
  • Molecular Weight: 417.37
  • Catalog: Signaling Pathways Cell Cycle/DNA Damage Nucleoside Antimetabolite/Analog
  • Create Date: 2018-06-22 17:07:54
  • Modify Date: 2024-01-11 10:08:03
  • N2-Phenoxyacetylguanosine is a guanosine analog. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7)[1].

Name Gua(pac)
Synonyms N2-phenoxyacetylguanosine
2-N-phenoxyacetylguanosine
2-N-(phenoxyacetyl)guanosine
N2-(phenoxyacetyl)guanosine
N-[9-((2R,3R,4S,5R)-3,4-Dihydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl]-2-phenoxy-acetamide
Description N2-Phenoxyacetylguanosine is a guanosine analog. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7)[1].
Related Catalog
References

[1]. Lee J, et al. Molecular basis for the immunostimulatory activity of guanine nucleoside analogs: activation of Toll-like receptor 7. Proc Natl Acad Sci U S A. 2003 May 27;100(11):6646-51.  

Density 1.76±0.1 g/cm3(Predicted)
Melting Point 159-160 °C
Molecular Formula C18H19N5O7
Molecular Weight 417.37
Exact Mass 417.12800
PSA 171.82000
Storage condition 2-8℃