62573-11-9

62573-11-9 structure

Name: Tos-PEG9
Chemical Name: nonaethyleneglycol mono(p-toluenesulfonyl) ether
CAS Number: 62573-11-9
Molecular Formula: C₂₅H₄₄O₁₂S
Molecular Weight: 568.67500
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2018-02-09 02:24:04
Modify Date: 2024-01-09 19:54:54
Tos-PEG9 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	nonaethyleneglycol mono(p-toluenesulfonyl) ether
Synonyms	26-hydroxy-3,6,9,12,15,18,21,24-octaoxahexacosyl p-toluenesulfonate

Description	Tos-PEG9 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562