190315-43-6

190315-43-6 structure

Name: (2R,3S,4R)-2-(Hydroxymethyl)tetrahydrothiophene-3,4-diol
Chemical Name: 1,4-anhydro-4-thio-D-ribitol
CAS Number: 190315-43-6
Molecular Formula: C₅H₁₀O₃S
Molecular Weight: 150.20
Catalog: Signaling Pathways Cell Cycle/DNA Damage Nucleoside Antimetabolite/Analog
Create Date: 2018-01-19 01:28:30
Modify Date: 2024-01-10 17:42:45
(2R,3S,4R)-2-(Hydroxymethyl)tetrahydrothiophene-3,4-diol is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Name	1,4-anhydro-4-thio-D-ribitol
Synonyms	(2R,3S,4R)-2-Hydroxymethyl-tetrahydro-thiophene-3,4-diol 1,4-anhydro-4-thio-D-ribose (+)-1-deoxy-4-thio-D-ribose

Description	(2R,3S,4R)-2-(Hydroxymethyl)tetrahydrothiophene-3,4-diol is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog
References	[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.