68422-20-8
68422-20-8 structure
- Name: Isocucurbitacin D
- Chemical Name: 3α,16α,20(R),25-tetrahydroxy-2,11,22-trioxocucurbita-5,23(E)-diene
- CAS Number: 68422-20-8
- Molecular Formula: C30H44O7
- Molecular Weight: 516.66600
- Catalog: Research Areas Cancer
- Create Date: 2018-03-08 14:57:32
- Modify Date: 2025-08-25 17:34:03
-
Isocucurbitacin D is an antitumor agent[1].
| Name | 3α,16α,20(R),25-tetrahydroxy-2,11,22-trioxocucurbita-5,23(E)-diene |
|---|---|
| Synonyms |
3-epi-isocucurbitacin D
(3S,8S,9R,10R,13R,14S,16R,17R)-17-((E)-(R)-1,5-Dihydroxy-1,5-dimethyl-2-oxo-hex-3-enyl)-3,16-dihydroxy-4,4,9,13,14-pentamethyl-3,4,7,8,9,10,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthrene-2,11-dione iso-cucurbitacin D Isocucurbitacin D isocucurbitacin D |
| Description | Isocucurbitacin D is an antitumor agent[1]. |
|---|---|
| Related Catalog | |
| In Vitro | Isocucurbitacin D 抑制癌细胞生长，对 SK-MEL-2、A549、XF498、HCT15 和 SK-OV-3 细胞的 ED50 分别为 0.06、0.2、0.6、0.8 和 1.2 μg/mL[1]。 Cell Proliferation Assay[1] Cell Line: MCF-7, MDA MB 231, A2780, A2780 CP, HepG2 and HCT-116 cells Concentration: 0-100 μM Incubation Time: 48 h Result: Inhibited cell proliferation with IC50s of 12.0, 30.7, 37.8, 47.9, >100 and >100 μM against MDA MB 231, HCT-116, HepG2, MCF-7, A2780 and A2780 CP, respectively. |
| References |
| Molecular Formula | C30H44O7 |
|---|---|
| Molecular Weight | 516.66600 |
| Exact Mass | 516.30900 |
| PSA | 132.13000 |
| LogP | 2.92850 |