49870-84-0

49870-84-0 structure

Name: Corydamine
Chemical Name: corydamine
CAS Number: 49870-84-0
Molecular Formula: C₂₀H₁₈N₂O₄
Molecular Weight: 350.36800
Create Date: 2018-04-14 08:00:00
Modify Date: 2025-08-20 15:49:29
Corydamine, 3-arylisoquinoline alkaloid, is a potent DNA topoisomerase I/II inhibitor. Corydamine has anti-cancer activity[1].

Name	corydamine
Synonyms	[2-(6-[1,3]Dioxolo[4,5-h]isoquinolin-7-yl-benzo[1,3]dioxol-5-yl)-ethyl]-methyl-amine [2-(6-[1,3]dioxolo[4,5-h]isoquinolin-7-yl-benzo[1,3]dioxol-5-yl)-ethyl]-methyl-amine Corydamin 2-[6-([1,3]dioxolo[4,5-h]isoquinolin-7-yl)-1,3-benzodioxol-5-yl]-N-methylethanamine

Description	Corydamine, 3-arylisoquinoline alkaloid, is a potent DNA topoisomerase I/II inhibitor. Corydamine has anti-cancer activity[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Topoisomerase
Target	Topoisomerase I Topoisomerase II
References	[1]. Xuemei Deng, et al. Design, synthesis and anti-hepatocellular carcinoma activity of 3-arylisoquinoline alkaloids. Eur J Med Chem. 2022 Jan 15;228:113985.