2033-08-1

2033-08-1 structure

Name: (±)-Coclaurine
Chemical Name: coclaurine
CAS Number: 2033-08-1
Molecular Formula: C₁₇H₁₉NO₃
Molecular Weight: 285.33800
Catalog: Research Areas Cardiovascular Disease
Create Date: 2018-04-22 04:44:04
Modify Date: 2024-01-23 10:05:59
(±)-Coclaurine is a natural product that can be found in Roemeria refracta. (±)-Coclaurine exhibits antioxidative activity and cardiovascular effects[1][2][3].

Name	coclaurine
Synonyms	1-(4-hydroxy-benzyl)-6-methoxy-1,2,3,4-tetrahydro-isoquinolin-7-ol D,L-coclaurine dl-coclaurine (R,S)-coclaurine (+/-)-coclaurine 1-(4-Hydroxy-benzyl)-6-methoxy-1,2,3,4-tetrahydro-isoquinolin-7-ol (+/-)-Coclaurine

Description	(±)-Coclaurine is a natural product that can be found in Roemeria refracta. (±)-Coclaurine exhibits antioxidative activity and cardiovascular effects[1][2][3].
Related Catalog	Research Areas >> Cardiovascular Disease Signaling Pathways >> Others >> Others
In Vitro	(±)-Coclaurine (1 μM-1 mM) 以浓度依赖性方式松弛 KCl 诱导的主动脉环收缩[3]。
References	[1]. Gözler B, et, al. Epimeric Isopavine N-Oxides from Roemeria refracta. Phytotherapy Research. Helvetica. 1992 Feb 5; 75(1): 260-268. [2]. Cassels BK, et, al. Structure-antioxidative activity relationships in benzylisoquinoline alkaloids. Pharmacol Res. 1995 Feb;31(2):103-7. [3]. Morales MA, et, al. Cardiovascular effects of plant secondary metabolites norarmepavine, coclaurine and norcoclaurine. Phytotherapy Research. 1998 Mar; 12(2): 103-109.