73971-79-6

73971-79-6 structure

Name: 1-(3-beta-Amino-2,3-dideoxy-beta-D-threopenta-furanosyl)thyMine
Chemical Name: 1-(1'-amino-2',3'-dideoxy-β-D-threo-pentofuranosyl)-5-methylpyrimidine-2,4(1H,3H)-dione
CAS Number: 73971-79-6
Molecular Formula: C₁₀H₁₅N₃O₄
Molecular Weight: 241.24
Catalog: Signaling Pathways Cell Cycle/DNA Damage Nucleoside Antimetabolite/Analog
Create Date: 2018-04-28 12:52:30
Modify Date: 2024-02-10 20:14:44
1-(3-Beta-amino-2,3-dideoxy-beta-d-threopenta-furanosyl)thymine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Name	1-(1'-amino-2',3'-dideoxy-β-D-threo-pentofuranosyl)-5-methylpyrimidine-2,4(1H,3H)-dione
Synonyms	1-((2R,4R,5S)-4-Amino-5-hydroxymethyl-tetrahydro-furan-2-yl)-5-methyl-1H-pyrimidine-2,4-dione 1-(3'-amino-2',3'-dideoxy-β-D-xylofuranosyl)thymidine 1-(3-Amino-2,3-dideoxy-β-D-threo-pentofuranosyl)thymine

Description	1-(3-Beta-amino-2,3-dideoxy-beta-d-threopenta-furanosyl)thymine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog
References	[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.