Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: N-[N-[N-(3-Hydroxy-4-methyl-1-oxooctyl)-L-tryptophyl]-L-phenylalanyl]-D-alloisoleucine λ-lactone
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

76265-41-3

76265-41-3 structure

Name: N-[N-[N-(3-Hydroxy-4-methyl-1-oxooctyl)-L-tryptophyl]-L-phenylalanyl]-D-alloisoleucine λ-lactone
Chemical Name: beauverolide Ja
CAS Number: 76265-41-3
Molecular Formula: C₃₅H₄₆N₄O₅
Molecular Weight: 602.76400
Catalog: Research Areas Neurological Disease
Create Date: 2018-06-20 08:26:09
Modify Date: 2024-02-24 09:34:26
Beauverolide Ja, a cyclotetradepsipeptide, is a potent calmodulin (CaM) inhibitor with a Kd of 0.078 μM and a Ki of 0.39 μM for Ca2+-CaM. Beauverolide Ja is a secondary metabolite of Isaria fumosorosea[1].

Name	beauverolide Ja
Synonyms	(3R,6S,9S)-6-Benzyl-3-((R)-sec-butyl)-9-(1H-indol-3-ylmethyl)-13-(1-methyl-pentyl)-1-oxa-4,7,10-triaza-cyclotridecane-2,5,8,11-tetraone

Description	Beauverolide Ja, a cyclotetradepsipeptide, is a potent calmodulin (CaM) inhibitor with a Kd of 0.078 μM and a Ki of 0.39 μM for Ca2+-CaM. Beauverolide Ja is a secondary metabolite of Isaria fumosorosea[1].
Related Catalog	Research Areas >> Neurological Disease
Target	Fungal Metabolite
References	[1]. Abraham Madariaga-Mazón, et al. Potent anti-calmodulin activity of cyclotetradepsipeptides isolated from Isaria fumosorosea using a newly designed biosensor. Nat Prod Commun. 2015 Jan;10(1):113-6. [2]. Qunfang Weng, et al. Secondary Metabolites and the Risks of Isaria fumosorosea and Isaria farinose. Molecules. 2019 Feb 13;24(4):664.