81348-83-6

81348-83-6 structure

Name: Momordicoside L
Chemical Name: (3β,7β,9β,10α,17β)-7-(β-D-glucopyranosyloxy)-3-hydroxy-17-[(3E)-5-hydroxy-1,5-dimethylhex-3-en-1-yl]-4,4,14-trimethylestr-5-ene-9-carboxaldehyde
CAS Number: 81348-83-6
Molecular Formula: C₃₆H₅₈O₉
Molecular Weight: 634.84000
Catalog: Research Areas Cancer
Create Date: 2018-03-08 08:00:00
Modify Date: 2024-01-10 11:25:51
Momordicoside L is a Cucurbitane Triterpenoid, that can be isolated from the leaves of Momordica charantia. Momordicoside L shows anticancer activity[1].

Name	(3β,7β,9β,10α,17β)-7-(β-D-glucopyranosyloxy)-3-hydroxy-17-[(3E)-5-hydroxy-1,5-dimethylhex-3-en-1-yl]-4,4,14-trimethylestr-5-ene-9-carboxaldehyde
Synonyms	3-hydroxy-17-(5-hydroxy-1,5-dimethyl-hex-3-enyl)-4,4,13,14-tetramethyl-7-(3,4,5-trihydroxy-6-hydroxymethyl-tetrahydro-pyran-2-yloxy)-1,2,3,4,7,8,10,11,12,13,14,15,16,17-tetradecahydro-cyclopenta[a]phenanthrene-9-carbaldehyde 3β,25-dihydroxy-19-oxo-cucurbita-5,23-diene-7β-yl β-D-glucopyranoside momordicoside K momordicoside L

Description	Momordicoside L is a Cucurbitane Triterpenoid, that can be isolated from the leaves of Momordica charantia. Momordicoside L shows anticancer activity[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Others >> Others
In Vitro	Momordicoside L 对 HL60（白血病）、CRL1579（黑色素瘤）、A549（肺）、SK-BR-3（乳腺）和 AZ521（胃）细胞显示出中度细胞毒性，IC50 值分别为 37.2 ± 2.7、11.9 ± 2.2、>50、>50 和 19.9 ± 1.5 μM[1]。
References	[1]. Zhang J, et al. Cucurbitane triterpenoids from the leaves of Momordica charantia, and their cancer chemopreventive effects and cytotoxicities. Chem Biodivers. 2012 Feb;9(2):428-40.