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1101668-39-6

1101668-39-6 structure
1101668-39-6 structure
  • Name: m-PEG4-propargyl
  • Chemical Name: 2,5,8,11,14-Pentaoxaheptadec-16-yne
  • CAS Number: 1101668-39-6
  • Molecular Formula: C12H22O5
  • Molecular Weight: 246.300
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2018-04-17 15:45:50
  • Modify Date: 2024-09-06 20:45:56
  • m-PEG4-propargyl is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.

Name 2,5,8,11,14-Pentaoxaheptadec-16-yne
Synonyms 2,5,8,11,14-Pentaoxaheptadec-16-yne
Description m-PEG4-propargyl is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
References

[1]. Lepage ML, et al. Design, synthesis and photochemical properties of the first examples of iminosugar clustersbased on fluorescent cores. Beilstein J Org Chem. 2015 May 6;11:659-67.

Density 1.0±0.1 g/cm3
Boiling Point 304.2±32.0 °C at 760 mmHg
Molecular Formula C12H22O5
Molecular Weight 246.300
Flash Point 115.2±25.0 °C
Exact Mass 246.146729
LogP -0.96
Vapour Pressure 0.0±0.6 mmHg at 25°C
Index of Refraction 1.443
Storage condition 2-8°C