1246298-48-5
1246298-48-5 structure
- Name: N-(2'-(S)-hydroxyarachidoyl)-D-erythro sphingosine
- Chemical Name: (2S)-N-[(2S,3R,4E)-1,3-Dihydroxy-4-octadecen-2-yl]-2-hydroxyicosanamide
- CAS Number: 1246298-48-5
- Molecular Formula: C38H75NO4
- Molecular Weight: 610.006
- Create Date: 2018-04-30 04:15:06
- Modify Date: 2023-02-03 19:21:33
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Hydroxy fatty acid (hFA)-sphingolipids help in formation and function of myelin. In addition, they also play a vital role in cell signaling, cell differentiation and apoptosis. In epidermis, hFA-ceramides aid in permeability barrier function. NAD(P)H-dependent enzyme, fatty acid 2-hydroxylase (FA2H) catalyzes the synthesis of hFA-ceramides. FA2H gene mutation leads to the development of neurological disorders such as leukodystrophy and spastic paraparesis in humans. hFA-ceramides help PM02734 (elisidepsin), an antitumor drug to exhibit its activity.
| Name | (2S)-N-[(2S,3R,4E)-1,3-Dihydroxy-4-octadecen-2-yl]-2-hydroxyicosanamide |
|---|---|
| Synonyms |
Eicosanamide, 2-hydroxy-N-[(1S,2R,3E)-2-hydroxy-1-(hydroxymethyl)-3-heptadecen-1-yl]-, (2S)-
(2S)-N-[(2S,3R,4E)-1,3-Dihydroxy-4-octadecen-2-yl]-2-hydroxyicosanamide |
| Density | 0.9±0.1 g/cm3 |
|---|---|
| Boiling Point | 739.3±60.0 °C at 760 mmHg |
| Molecular Formula | C38H75NO4 |
| Molecular Weight | 610.006 |
| Flash Point | 400.9±32.9 °C |
| Exact Mass | 609.569580 |
| LogP | 14.95 |
| Vapour Pressure | 0.0±5.5 mmHg at 25°C |
| Index of Refraction | 1.486 |
| Storage condition | 20°C |