1246298-48-5

1246298-48-5 structure
1246298-48-5 structure
  • Name: N-(2'-(S)-hydroxyarachidoyl)-D-erythro sphingosine
  • Chemical Name: (2S)-N-[(2S,3R,4E)-1,3-Dihydroxy-4-octadecen-2-yl]-2-hydroxyicosanamide
  • CAS Number: 1246298-48-5
  • Molecular Formula: C38H75NO4
  • Molecular Weight: 610.006
  • Create Date: 2018-04-30 04:15:06
  • Modify Date: 2023-02-03 19:21:33
  • Hydroxy fatty acid (hFA)-sphingolipids help in formation and function of myelin. In addition, they also play a vital role in cell signaling, cell differentiation and apoptosis. In epidermis, hFA-ceramides aid in permeability barrier function. NAD(P)H-dependent enzyme, fatty acid 2-hydroxylase (FA2H) catalyzes the synthesis of hFA-ceramides. FA2H gene mutation leads to the development of neurological disorders such as leukodystrophy and spastic paraparesis in humans. hFA-ceramides help PM02734 (elisidepsin), an antitumor drug to exhibit its activity.

Name (2S)-N-[(2S,3R,4E)-1,3-Dihydroxy-4-octadecen-2-yl]-2-hydroxyicosanamide
Synonyms Eicosanamide, 2-hydroxy-N-[(1S,2R,3E)-2-hydroxy-1-(hydroxymethyl)-3-heptadecen-1-yl]-, (2S)-
(2S)-N-[(2S,3R,4E)-1,3-Dihydroxy-4-octadecen-2-yl]-2-hydroxyicosanamide
Density 0.9±0.1 g/cm3
Boiling Point 739.3±60.0 °C at 760 mmHg
Molecular Formula C38H75NO4
Molecular Weight 610.006
Flash Point 400.9±32.9 °C
Exact Mass 609.569580
LogP 14.95
Vapour Pressure 0.0±5.5 mmHg at 25°C
Index of Refraction 1.486
Storage condition 20°C