97612-24-3

97612-24-3 structure

Name: FLB 131
Chemical Name: S-(-)-Eticlopride hydrochloride
CAS Number: 97612-24-3
Molecular Formula: C₁₇H₂₆Cl₂N₂O₃
Molecular Weight: 377.306
Catalog: Signaling Pathways GPCR/G Protein Dopamine Receptor
Create Date: 2018-08-19 19:58:16
Modify Date: 2025-08-27 12:18:27
Eticlopride hydrochloride, a selective dopamine D2‐like receptor antagonist, exhibits high affinity for dopamine D2, α1‐adrenergic, α2‐adrenergic, 5HT1, 5HT2 receptors with Kis of 0.09, 112, 699, 6220, and 830 nM, respectively. Antipsychotic agent[1].

Name	S-(-)-Eticlopride hydrochloride
Synonyms	(2S)-2-{[(3-Chloro-5-ethyl-6-hydroxy-2-methoxybenzoyl)amino]methyl}-1-ethylpyrrolidinium chloride 3-Chloro-5-ethyl-N-{[(2S)-1-ethylpyrrolidin-2-yl]methyl}-6-hydroxy-2-methoxybenzamide hydrochloride (1:1) Pyrrolidinium, 2-[[(3-chloro-5-ethyl-6-hydroxy-2-methoxybenzoyl)amino]methyl]-1-ethyl-, chloride, (2S)- (1:1) MFCD00055132

Description	Eticlopride hydrochloride, a selective dopamine D2‐like receptor antagonist, exhibits high affinity for dopamine D2, α1‐adrenergic, α2‐adrenergic, 5HT1, 5HT2 receptors with Kis of 0.09, 112, 699, 6220, and 830 nM, respectively. Antipsychotic agent[1].
Related Catalog	Signaling Pathways >> GPCR/G Protein >> Dopamine Receptor Signaling Pathways >> Neuronal Signaling >> Dopamine Receptor Research Areas >> Neurological Disease
Target	D2 Receptor:0.09 nM (Ki)
References	[1]. Jennifer L Martelle, et al. A review of the discovery, pharmacological characterization, and behavioral effects of the dopamine D2-like receptor antagonist eticlopride. CNS Neurosci Ther. Fall 2008;14(3):248-62.

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADR	NONH for all modes of transport
RTECS	CV2450000