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1354825-62-9

1354825-62-9 structure
1354825-62-9 structure
  • Name: WEHI-345 analog
  • Chemical Name: WEHI-345 analog
  • CAS Number: 1354825-62-9
  • Molecular Formula: C23H25N7O
  • Molecular Weight: 415.491
  • Catalog: Signaling Pathways Protein Tyrosine Kinase/RTK Src
  • Create Date: 2018-05-10 08:55:35
  • Modify Date: 2024-01-02 17:12:46
  • WEHI-345 (analog) is a Src inhibitor, extracted from patent WO/2012003544A1, compound example 71.Target:SrcWEHI-345 (analog) is a protein kinase inhibitor. A family of proto-oncogenic TPKs referred to herein as SFKs (Src family kinases) have provided researchers with a better understanding of the mechanism of cancer as a disease state where normally healthy cellular signalling is disrupted.

Name WEHI-345 analog
Synonyms N-{2-[4-Amino-3-(4-methylphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-2-methylpropyl}-3-methyl-2-pyridinecarboxamide
2-Pyridinecarboxamide, N-[2-[4-amino-3-(4-methylphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-2-methylpropyl]-3-methyl-
Description WEHI-345 (analog) is a Src inhibitor, extracted from patent WO/2012003544A1, compound example 71.Target:SrcWEHI-345 (analog) is a protein kinase inhibitor. A family of proto-oncogenic TPKs referred to herein as SFKs (Src family kinases) have provided researchers with a better understanding of the mechanism of cancer as a disease state where normally healthy cellular signalling is disrupted.
Related Catalog
References

[1]. Jonathan Bayldon Baell, et al. Protein kinase inhibitors and methods of treatment. WO2012003544A1.

Density 1.3±0.1 g/cm3
Boiling Point 688.0±55.0 °C at 760 mmHg
Molecular Formula C23H25N7O
Molecular Weight 415.491
Flash Point 369.9±31.5 °C
Exact Mass 415.212067
LogP 2.76
Vapour Pressure 0.0±2.1 mmHg at 25°C
Index of Refraction 1.678
Storage condition 2-8℃