1219804-15-5

1219804-15-5 structure

Name: 3-(Cyclohexylamino)-1-propanesulfonic Acid-d17
Chemical Name: 3-(CyclohexylaMino)-1-propanesulfonic-d17 Acid
CAS Number: 1219804-15-5
Molecular Formula: C₉H₂D₁₇NO₃S
Molecular Weight: 238.422
Catalog: Research Areas Others
Create Date: 2018-06-30 18:57:34
Modify Date: 2024-01-08 09:30:18
3-(Cyclohexylamino)-1-propanesulfonic Acid-d17 is the deuterium labeled CAPS[1]. CAPS, cyclohexylaminopropane sulfonic acid, is a surfactant. CAPS can be used as biological buffer (0.05 M, pH 11) for dialysis[2][3].

Name	3-(CyclohexylaMino)-1-propanesulfonic-d17 Acid
Synonyms	3-[(2H11)Cyclohexylamino]-1-(2H6)propanesulfonic acid 1-Propane-1,1,2,2,3,3-d6-sulfonic acid, 3-(cyclohexyl-d11-amino)- 3-[(2H11)Cyclohexylamino](2H6)propane-1-sulfonic acid

Description	3-(Cyclohexylamino)-1-propanesulfonic Acid-d17 is the deuterium labeled CAPS[1]. CAPS, cyclohexylaminopropane sulfonic acid, is a surfactant. CAPS can be used as biological buffer (0.05 M, pH 11) for dialysis[2][3].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [2]. Bedard P R, et al. Ion Interaction: The Energetics and Mechanism of The Competitive Behavior Between Two Similarly Charged Molecules. 1. The Effect of Ionic Strength, Acetonitrile and Surfactant Concentration[J]. Journal of Liquid Chromatography, 1985, 8(13):2417-2443. [3]. Oberley TD, et al. The effect of the dimeric and multimeric forms of fibronectin on the adhesion and growth of primary glomerular cells. Exp Cell Res. 1983 May145(2):265-76.