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179986-93-7

179986-93-7 structure

179986-93-7 structure

Name: (Pro34)-Peptide YY (human) trifluoroacetate salt
Chemical Name: (Pro34)-Peptide YY (huMan)
CAS Number: 179986-93-7
Molecular Formula: C₁₉₄H₂₉₄N₅₄O₅₆
Molecular Weight:
Catalog: Signaling Pathways GPCR/G Protein Neuropeptide Y Receptor
Create Date: 2018-05-09 19:42:50
Modify Date: 2024-01-12 20:51:07
(Pro34)-Peptide YY (human) is a highly Y1-selective full agonist of Peptide YY (HY-P1514)/neuropeptide Y receptors[1].

Name	(Pro34)-Peptide YY (huMan)
Synonyms	YPIKPEAPGEDASPEELNRYYASLRHYLNLVTRPRY-NH2 Tyr-Pro-Ile-Lys-Pro-Glu-Ala-Pro-Gly-Glu-Asp-Ala-Ser-Pro-Glu-Glu-Leu-Asn-Arg-Tyr-Tyr-Ala-Ser-Leu-Arg-His-Tyr-Leu-Asn-Leu-Val-Thr-Arg-Pro-Arg-Tyr-NH2

Description	(Pro34)-Peptide YY (human) is a highly Y1-selective full agonist of Peptide YY (HY-P1514)/neuropeptide Y receptors[1].
Related Catalog	Research Areas >> Neurological Disease Signaling Pathways >> GPCR/G Protein >> Neuropeptide Y Receptor
Target	NPY Y1 receptor
In Vitro	(Pro34)-Peptide YY (human) 在完整的 SK-N-MC 和 HEL 细胞 (Y1 样亚型) 和猪脾膜 (Y2 样亚型) 中竞争所有特定的 [125I] 神经肽 Y 结合位点。(Pro34)-Peptide YY 在完整的 SK-N-MC 和 HEL 细胞中的亲和力 (pKi 分别为 7.8 ± 0.2 和 8.2 ± 0.1) 与 Peptide YY (pKi 分别为 8.5 ± 0.1 和 8.6 ± 0.1) 非常相似[1]。
References	[1]. Grandt D, et al. [Pro34]peptide YY is a Y1-selective agonist at peptide YY/neuropeptide Y receptors. Eur J Pharmacol. 1994 Oct 14;269(2):127-32.

Molecular Formula	C₁₉₄H₂₉₄N₅₄O₅₆

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