1321514-06-0

1321514-06-0 structure

Name: AZD-4635
Chemical Name: 6-(2-chloro-6-methylpyridin-4-yl)-5-(4-fluorophenyl)-1,2,4-triazin-3-amine
CAS Number: 1321514-06-0
Molecular Formula: C₁₅H₁₁ClFN₅
Molecular Weight: 315.73300
Catalog: Signaling Pathways GPCR/G Protein Adenosine Receptor
Create Date: 2018-04-12 08:35:20
Modify Date: 2025-08-25 19:19:15
AZD4635 is a novel adenosine 2A receptor (A2AR) inhibitor with a Ki of 1.7 nM.

Name	6-(2-chloro-6-methylpyridin-4-yl)-5-(4-fluorophenyl)-1,2,4-triazin-3-amine
Synonyms	AZD-4635 AZD4635 6-(2-Chloro-6-methyl-4-pyridinyl)-5-(4-fluorophenyl)-1,2,4-triazin-3-amine

Description	AZD4635 is a novel adenosine 2A receptor (A2AR) inhibitor with a Ki of 1.7 nM.
Related Catalog	Signaling Pathways >> GPCR/G Protein >> Adenosine Receptor Research Areas >> Cancer
Target	Ki: 1.7 nM (A2AR)
References	[1]. Alexandra Borodovsky, et al. Abstract 5580: Preclinical pharmacodynamics and antitumor activity of AZD4635, a novel adenosine 2A receptor inhibitor that reverses adenosine mediated T cell suppression. AACR; Cancer Res 2017;77(13 Suppl):Abstract nr 5580.