88901-43-3

88901-43-3 structure

Name: Mogroside III-A2
Chemical Name: Mogroside III A2
CAS Number: 88901-43-3
Molecular Formula: C₄₈H₈₂O₁₉
Molecular Weight: 963.153
Catalog: Signaling Pathways Anti-infection HSV
Create Date: 2018-11-30 21:03:33
Modify Date: 2024-01-05 11:11:56
Mogroside III A2 is a cucurbitane glycoside. Mogroside III A2 can inhibit Epstein-Barr virus early antigen (EBV-EA) activation. Mogroside III A2 shows weak inhibitory effects on activation of NOR 1[1].

Name	Mogroside III A2
Synonyms	β-D-glucopyranoside, (1R,4R)-4-[(3β,9β,10α,11α,17β)-3-[(6-O-β-D-glucopyranosyl-β-D-glucopyranosyl)oxy]-11-hydroxy-4,4,9,14-tetramethylestr-5-en-17-yl]-1-(1-hydroxy-1-methylethyl)pentyl β-D-Glucopyranoside, (1R,4R)-4-[(3β,9β,10α,11α,17β)-3-[(6-O-β-D-glucopyranosyl-β-D-glucopyranosyl)oxy]-11-hydroxy-4,4,9,14-tetramethylestr-5-en-17-yl]-1-(1-hydroxy-1-methylet hyl)pentyl (1S,4R,9β,11α,24R)-1-{[6-O-(β-D-Glucopyranosyl)-β-D-glucopyranosyl]oxy}-11,25-dihydroxy-9,10,14-trimethyl-4,9-cyclo-9,10-secocholest-5-en-24-yl β-D-glucopyranoside

Description	Mogroside III A2 is a cucurbitane glycoside. Mogroside III A2 can inhibit Epstein-Barr virus early antigen (EBV-EA) activation. Mogroside III A2 shows weak inhibitory effects on activation of NOR 1[1].
Related Catalog	Signaling Pathways >> Anti-infection >> HSV Research Areas >> Infection
Target	Epstein-Barr virus[1]
In Vitro	Mogroside III A2 inhibits the Epstein-Barr virus early antigen (EBV-EA) activation induced by 12-O-tetradecanoylphorbol-13-acetate (TPA), with IC50 of 352 mol ratio/32 pmol TPA[1]. Mogroside III A2 shows weak inhibitory effects on activation of (±)-(E)-methyl-2-[(E)-hydroxyimino]-5-nitro-6-methoxy-3-hexemide (NOR 1)[1].
References	[1]. Akihisa T, et, al. Cucurbitane glycosides from the fruits of Siraitia gros venorii and their inhibitory effects on Epstein-Barr virus activation. J Nat Prod. 2007 May;70(5):783-8.