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1351927-00-8

1351927-00-8 structure
1351927-00-8 structure
  • Name: T338C Src-IN-2
  • Chemical Name: T338C Src-IN-2
  • CAS Number: 1351927-00-8
  • Molecular Formula: C17H18FN5O
  • Molecular Weight: 327.356
  • Catalog: Signaling Pathways Protein Tyrosine Kinase/RTK Src
  • Create Date: 2018-06-24 23:42:55
  • Modify Date: 2024-01-12 11:43:38
  • T338C Src-IN-2 is a potent mutant c-Src T338C kinase inhibitor with IC50 of 317 nM; also inhibits T338C/V323A and T338C/V323S with IC50 of 57 nM/19 nM.

Name T338C Src-IN-2
Synonyms 1-{3-[(4-Amino-1-isopropyl-1H-pyrazolo[3,4-d]pyrimidin-3-yl)methyl]phenyl}-2-fluoroethanone
Ethanone, 1-[3-[[4-amino-1-(1-methylethyl)-1H-pyrazolo[3,4-d]pyrimidin-3-yl]methyl]phenyl]-2-fluoro-
Description T338C Src-IN-2 is a potent mutant c-Src T338C kinase inhibitor with IC50 of 317 nM; also inhibits T338C/V323A and T338C/V323S with IC50 of 57 nM/19 nM.
Related Catalog
References

[1]. Garske AL, et al. Chemical genetic strategy for targeting protein kinases based on covalent complementarity. Proc Natl Acad Sci U S A. 2011 Sep 13;108(37):15046-52.

Density 1.4±0.1 g/cm3
Boiling Point 540.6±50.0 °C at 760 mmHg
Molecular Formula C17H18FN5O
Molecular Weight 327.356
Flash Point 280.8±30.1 °C
Exact Mass 327.149536
LogP 1.54
Vapour Pressure 0.0±1.4 mmHg at 25°C
Index of Refraction 1.657
Storage condition 2-8℃