Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: (+-)-4-Diethylamino-1,1-dimethylbut-2-yn-1-yl 2-cyclohexyl-2-hydroxy-2-phenylacetate HCl H2O
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136529-33-4

136529-33-4 structure

136529-33-4 structure

Name: Temiverine hydrochloride
Chemical Name: Temiverine hydrochloride
CAS Number: 136529-33-4
Molecular Formula: C₂₄H₃₆ClNO₃
Molecular Weight: 422.000
Catalog: Signaling Pathways GPCR/G Protein mAChR
Create Date: 2018-05-28 08:25:56
Modify Date: 2024-01-02 10:19:41
Temiverine hydrochloride is a synthesized drug that is expected to have anticholinergic action.

Name	Temiverine hydrochloride
Synonyms	Temiverine hydrochloride 5-(Diethylamino)-2-methyl-3-pentyn-2-yl cyclohexyl(hydroxy)phenylacetate hydrochloride (1:1) Benzeneacetic acid, α-cyclohexyl-α-hydroxy-, 4-(diethylamino)-1,1-dimethyl-2-butyn-1-yl ester, hydrochloride (1:1) UNII:24II7HX270

Description	Temiverine hydrochloride is a synthesized drug that is expected to have anticholinergic action.
Related Catalog	Signaling Pathways >> GPCR/G Protein >> mAChR Signaling Pathways >> Neuronal Signaling >> mAChR Research Areas >> Neurological Disease
Target	Anticholinergic[1]
In Vitro	Atropine (1 nM to 1 μM), Oxybutynin (10 nM to 10 μM), Temiverine (10 nM to 10 μM), and RCC-36 (10 nM to 1 μM) cause a parallel shift to the right of the concentration-response curves to acetylcholine stimulation[1].
References	[1]. Kikukawa H, et al. Pharmacologic actions of temiverine (p-INN) and its active metabolite, RCC-36, on isolated human urinary bladder muscle. Int J Urol. 1998 May;5(3):268-75.

Molecular Formula	C₂₄H₃₆ClNO₃
Molecular Weight	422.000
Exact Mass	421.238373