1411977-95-1
1411977-95-1 structure
- Name: Acetylene-linker-Val-Cit-PABC-MMAE
- Chemical Name: Acetylene-linker-Val-Cit-PABC-MMAE
- CAS Number: 1411977-95-1
- Molecular Formula: C67H106N10O16
- Molecular Weight: 1307.616
- Catalog: Signaling Pathways Antibody-drug Conjugate Drug-Linker Conjugates for ADC
- Create Date: 2018-02-21 00:56:49
- Modify Date: 2024-01-03 16:45:36
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Acetylene-linker-Val-Cit-PABC-MMAE consists the ADCs linker (Acetylene-linker-Val-Cit-PABC) and potent tubulin inhibitor (MMAE), Acetylene-linker-Val-Cit-PABC-MMAE is an antibody drug conjugate.
| Name | Acetylene-linker-Val-Cit-PABC-MMAE |
|---|---|
| Synonyms |
L-Ornithinamide, N-[2-[2-[2-(2-propyn-1-yloxy)ethoxy]ethoxy]acetyl]-L-valyl-N5-(aminocarbonyl)-N-[4-[(5S,8S,11S,12R)-12-[2-[(2S)-2-[(1R,2R)-3-[[(1R,2S)-2-hydroxy-1-methyl-2-phenylethyl]amino]-1-meth oxy-2-methyl-3-oxopropyl]-1-pyrrolidinyl]-2-oxoethyl]-4,10-dimethyl-5,8-bis(1-methylethyl)-11-[(1S)-1-methylpropyl]-3,6,9-trioxo-2,13-dioxa-4,7,10-triazatetradec-1-yl]phenyl]-
N-({2-[2-(2-Propyn-1-yloxy)ethoxy]ethoxy}acetyl)-L-valyl-N-{4-[(5S,8S,11S,12R)-11-[(2S)-2-butanyl]-12-(2-{(2S)-2-[(1R,2R)-3-{[(1S,2R)-1-hydroxy-1-phenyl-2-propanyl]amino}-1-methoxy-2-methyl-3-oxopropy ;l]-1-pyrrolidinyl}-2-oxoethyl)-5,8-diisopropyl-4,10-dimethyl-3,6,9-trioxo-2,13-dioxa-4,7,10-triazatetradec-1-yl]phenyl}-N5-carbamoyl-L-ornithinamide LCB14-0602 |
| Description | Acetylene-linker-Val-Cit-PABC-MMAE consists the ADCs linker (Acetylene-linker-Val-Cit-PABC) and potent tubulin inhibitor (MMAE), Acetylene-linker-Val-Cit-PABC-MMAE is an antibody drug conjugate. |
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| Related Catalog | |
| References |
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Boiling Point | 1312.0±65.0 °C at 760 mmHg |
| Molecular Formula | C67H106N10O16 |
| Molecular Weight | 1307.616 |
| Flash Point | 747.3±34.3 °C |
| Exact Mass | 1306.778809 |
| LogP | 5.33 |
| Vapour Pressure | 0.0±0.3 mmHg at 25°C |
| Index of Refraction | 1.544 |
| Storage condition | 2-8℃ |