1629268-19-4
1629268-19-4 structure
- Name: K-Ras G12C-IN-3
- Chemical Name: K-Ras G12C-IN-3
- CAS Number: 1629268-19-4
- Molecular Formula: C21H19Cl3N2O3
- Molecular Weight: 453.746
- Catalog: Signaling Pathways GPCR/G Protein Ras
- Create Date: 2018-04-06 19:18:45
- Modify Date: 2024-01-19 11:07:18
-
K-Ras G12C-IN-3 is a novel and irreversible inhibitor of mutant K-ras G12C.IC50 value:Target: K-ras G12C inhibitorFor more information, please see the following patent.Heterocyclic compounds as covalent inhibitors of G12C mutant K-Ras protein useful for treating cancers, and preparation thereofBy Ren, Pingda; Liu, Yi; Li, Liansheng; Feng, Jun; Wu, Tao From PCT Int. Appl. (2014), WO 2014152588 A1 20140925.
| Name | K-Ras G12C-IN-3 |
|---|---|
| Synonyms |
2-Propen-1-one, 1-[4-[(2',5',6-trichloro-4-methoxy[1,1'-biphenyl]-3-yl)carbonyl]-1-piperazinyl]-
1-{4-[(2',5',6-Trichloro-4-methoxy-3-biphenylyl)carbonyl]-1-piperazinyl}-2-propen-1-one |
| Description | K-Ras G12C-IN-3 is a novel and irreversible inhibitor of mutant K-ras G12C.IC50 value:Target: K-ras G12C inhibitorFor more information, please see the following patent.Heterocyclic compounds as covalent inhibitors of G12C mutant K-Ras protein useful for treating cancers, and preparation thereofBy Ren, Pingda; Liu, Yi; Li, Liansheng; Feng, Jun; Wu, Tao From PCT Int. Appl. (2014), WO 2014152588 A1 20140925. |
|---|---|
| Related Catalog |
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Boiling Point | 655.0±55.0 °C at 760 mmHg |
| Molecular Formula | C21H19Cl3N2O3 |
| Molecular Weight | 453.746 |
| Flash Point | 349.9±31.5 °C |
| Exact Mass | 452.046112 |
| LogP | 3.39 |
| Vapour Pressure | 0.0±2.0 mmHg at 25°C |
| Index of Refraction | 1.604 |
| Storage condition | 2-8℃ |