108226-05-7

108226-05-7 structure

108226-05-7 structure

Name: Benzamide Derivative 1
Chemical Name: Benzamide Derivative 1
CAS Number: 108226-05-7
Molecular Formula: C₂₂H₃₄ClN₃O₃
Molecular Weight: 423.98
Catalog: Signaling Pathways GPCR/G Protein Dopamine Receptor
Create Date: 2018-01-13 17:17:53
Modify Date: 2024-01-04 14:55:51
Benzamide Derivative 1 is a benzamide derivative from patent EP0213775A1, compound 18. Benzamide Derivative 1 may be useful in treatment of gastrointestinal disorders.

Name	Benzamide Derivative 1

Description	Benzamide Derivative 1 is a benzamide derivative from patent EP0213775A1, compound 18. Benzamide Derivative 1 may be useful in treatment of gastrointestinal disorders.
Related Catalog	Signaling Pathways >> GPCR/G Protein >> Dopamine Receptor Signaling Pathways >> Neuronal Signaling >> Dopamine Receptor Signaling Pathways >> GPCR/G Protein >> mAChR Signaling Pathways >> Neuronal Signaling >> mAChR Research Areas >> Neurological Disease
Target	Dopamine, mACh receptor[1]
In Vitro	Substituted benzamides have been shown to possess a number of pharmacological properties most of which are related to their ability to antagonize the central and peripheral effects of dopamine and/or facilitate the release of acetylcholine on to muscarinic receptors in the gastrointestinal smooth muscle. This has led to their successful clinical use as antiemetic and in the treatment of a wide range of gastrointestinal disorders of somatic, psychosomatic and iatrogenic origin[1].
References	[1]. Noverola V, et al. Preparation and formulation of N-heterocyclyl-substituted benzamides useful in treatment of gastrointestinal disorders. EP0213775A1.

Molecular Formula	C₂₂H₃₄ClN₃O₃
Molecular Weight	423.98