108226-05-7

108226-05-7 structure
108226-05-7 structure
  • Name: Benzamide Derivative 1
  • Chemical Name: Benzamide Derivative 1
  • CAS Number: 108226-05-7
  • Molecular Formula: C22H34ClN3O3
  • Molecular Weight: 423.98
  • Catalog: Signaling Pathways GPCR/G Protein Dopamine Receptor
  • Create Date: 2018-01-13 17:17:53
  • Modify Date: 2025-08-25 11:07:43
  • Benzamide Derivative 1 is a benzamide derivative from patent EP0213775A1, compound 18. Benzamide Derivative 1 may be useful in treatment of gastrointestinal disorders.

Name Benzamide Derivative 1
Description Benzamide Derivative 1 is a benzamide derivative from patent EP0213775A1, compound 18. Benzamide Derivative 1 may be useful in treatment of gastrointestinal disorders.
Related Catalog
Target

Dopamine, mACh receptor[1]

In Vitro Substituted benzamides have been shown to possess a number of pharmacological properties most of which are related to their ability to antagonize the central and peripheral effects of dopamine and/or facilitate the release of acetylcholine on to muscarinic receptors in the gastrointestinal smooth muscle. This has led to their successful clinical use as antiemetic and in the treatment of a wide range of gastrointestinal disorders of somatic, psychosomatic and iatrogenic origin[1].
References

[1]. Noverola V, et al. Preparation and formulation of N-heterocyclyl-substituted benzamides useful in treatment of gastrointestinal disorders. EP0213775A1.

Molecular Formula C22H34ClN3O3
Molecular Weight 423.98
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