148498-78-6

148498-78-6 structure
148498-78-6 structure
  • Name: Adrenomedullin (human)
  • Chemical Name: Adrenomedullin (AM) (1-52), human
  • CAS Number: 148498-78-6
  • Molecular Formula: C264H406N80O77S3
  • Molecular Weight: 6028.82
  • Catalog: Peptides
  • Create Date: 2018-04-19 04:38:37
  • Modify Date: 2024-01-02 10:29:56
  • Adrenomedullin (AM) (1-52), human is a 52-amino acid peptide, which affects cell proliferation and angiogenesis in cancer.

Name Adrenomedullin (AM) (1-52), human
Description Adrenomedullin (AM) (1-52), human is a 52-amino acid peptide, which affects cell proliferation and angiogenesis in cancer.
Related Catalog
In Vitro To explore the effect of Adrenomedullin (AM) (1-52), human on astroglioma cells, CRT-MG cells are incubated in the absence or presence of Adrenomedullin (AM) (1-52), human (ADM1-52) for 48 h in a medium containing 1% FBS, and wound-healing assay is performed. The number of cells migrating to the wound region significantly increases in the ADM1-52-treated cells, in a dose-dependent manner, compared to the untreated cells[1].
Cell Assay CRT-MG cells are scraped off the bottom of a culture plate using a pipette tip to create a cell-free area. The cell culture is washed with PBS to remove cell debris and then incubated with oncostatin M (OSM), Adrenomedullin (AM) (1-52), human (ADM1-52; 0.1 μM and 0.5 μM) for 48 h in 1% FBS DMEM. The wound area is photographed after scratching for control. The number of cells migrating into the initial wound area is counted at 48 h after scratching[1].
References

[1]. Lim SY, et al. Transcriptional regulation of adrenomedullin by oncostatin M in human astroglioma cells: implications for tumor invasion and migration. Sci Rep. 2014 Sep 23;4:6444.

Molecular Formula C264H406N80O77S3
Molecular Weight 6028.82
Appearance powder
Storage condition −20°C
Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADR NONH for all modes of transport
WGK Germany 3
RTECS AV6800000