1802226-78-3

1802226-78-3 structure

Name: PSB-12379
Chemical Name: PSB-12379
CAS Number: 1802226-78-3
Molecular Formula: C₁₈H₂₃N₅O₉P₂
Molecular Weight: 515.35
Catalog: Signaling Pathways GPCR/G Protein Adenosine Receptor
Create Date: 2018-06-26 10:25:00
Modify Date: 2024-01-02 18:01:49
PSB-12379 is a potent Ecto-5'-Nucleotidase (CD73) inhibitor with Kis of 9.03 nM (rat) and 2.21 nM (human).

Name	PSB-12379

Description	PSB-12379 is a potent Ecto-5'-Nucleotidase (CD73) inhibitor with Kis of 9.03 nM (rat) and 2.21 nM (human).
Related Catalog	Signaling Pathways >> GPCR/G Protein >> Adenosine Receptor Research Areas >> Cancer
Target	Ki: 9.03 nM (rat), 2.21 nM (human) (Ecto-5’-Nucleotidase)[1]
References	[1]. Bhattarai S, et al. α,β-Methylene-ADP (AOPCP) Derivatives and Analogues: Development of Potent and Selective ecto-5'-Nucleotidase (CD73) Inhibitors. J Med Chem. 2015 Aug 13;58(15):6248-63.