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854601-80-2

854601-80-2 structure
854601-80-2 structure
  • Name: m-PEG5-Br
  • Chemical Name: 16-Bromo-2,5,8,11,14-pentaoxahexadecane
  • CAS Number: 854601-80-2
  • Molecular Formula: C11H23BrO5
  • Molecular Weight: 315.201
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2018-07-20 11:24:47
  • Modify Date: 2024-01-09 20:43:13
  • m-PEG5-Br is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].

Name 16-Bromo-2,5,8,11,14-pentaoxahexadecane
Synonyms 16-Bromo-2,5,8,11,14-pentaoxahexadecane
2,5,8,11,14-Pentaoxahexadecane, 16-bromo-
Description m-PEG5-Br is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. Jennifer Riggs-Sauthier, et al. Oligomer-Protein Tyrosine Kinase Inhibitor Conjugates. US20120094998A1.

Density 1.2±0.1 g/cm3
Boiling Point 342.4±32.0 °C at 760 mmHg
Molecular Formula C11H23BrO5
Molecular Weight 315.201
Flash Point 139.3±23.6 °C
Exact Mass 314.072876
LogP -0.54
Vapour Pressure 0.0±0.7 mmHg at 25°C
Index of Refraction 1.457