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16958-29-5

16958-29-5 structure
16958-29-5 structure
  • Name: Otosenine
  • Chemical Name: otosenine
  • CAS Number: 16958-29-5
  • Molecular Formula: C19H27NO7
  • Molecular Weight: 381.42
  • Create Date: 2018-07-10 19:49:32
  • Modify Date: 2025-08-25 13:50:22
  • Otosenine is a natural pyrrolizidine alkaloid. Otosenine can be isolated from the aerial parts of the golden ragwort, Senecio aureus. Otosenine has spasmolytic and hypotensive properties[1][2].

Name otosenine
Synonyms (1R,3'S,4S,6R,7R,11Z)-7-Hydroxy-3',6,7,14-tetramethyl-8H,17H-spiro[2,9-dioxa-14-azabicyclo[9.5.1]heptadec-11-ene-4,2'-oxirane]-3,8,17-trione
otosenine
Spiro[2,9-dioxa-14-azabicyclo[9.5.1]heptadec-11-ene-4,2'-oxirane]-3,8,17-trione, 7-hydroxy-3',6,7,14-tetramethyl-, (1R,3'S,4S,6R,7R,11Z)-
Z999A1E7I4
Description Otosenine is a natural pyrrolizidine alkaloid. Otosenine can be isolated from the aerial parts of the golden ragwort, Senecio aureus. Otosenine has spasmolytic and hypotensive properties[1][2].
Related Catalog
References

[1]. Resch J F, et al. Otosenine from Senecio aureus[J]. Planta medica, 1983, 47(04): 255-255.

[2]. Lee S, et al. Isolation and biological activity of azocine and azocane alkaloids. Bioorg Med Chem. 2022 Jan 15;54:116560.  

Density 1.3±0.1 g/cm3
Boiling Point 614.7±55.0 °C at 760 mmHg
Molecular Formula C19H27NO7
Molecular Weight 381.42
Flash Point 325.6±31.5 °C
Exact Mass 381.178741
LogP -0.56
Vapour Pressure 0.0±4.0 mmHg at 25°C
Index of Refraction 1.557
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