956707-04-3

956707-04-3 structure

Name: 8beta,9alpha-Dihydroxylindan-4(5),7(11)-dien-8alpha,12-olide
Chemical Name: (5aS,6aR,6bS,7S,7aR)-7,7a-Dihydroxy-3,5,6b-trimethyl-5a,6,6a,6b,7,7a-hexahydrocyclopropa[2,3]indeno[5,6-b]furan-2(4H)-one
CAS Number: 956707-04-3
Molecular Formula: C₁₅H₁₈O₄
Molecular Weight: 262.301
Catalog: Signaling Pathways Cell Cycle/DNA Damage LIM Kinase (LIMK)
Create Date: 2018-07-09 14:48:18
Modify Date: 2024-01-31 20:03:44
8β,9α-Dihydroxylindan-4(5),7(11)-dien-8alpha,12-olide (compound 3), a sesquiterpene, has anti-LIMK1 activity. 8β,9α-Dihydroxylindan-4(5),7(11)-dien-8alpha,12-olide has inhibitory property on cell motility[1].

Name	(5aS,6aR,6bS,7S,7aR)-7,7a-Dihydroxy-3,5,6b-trimethyl-5a,6,6a,6b,7,7a-hexahydrocyclopropa[2,3]indeno[5,6-b]furan-2(4H)-one
Synonyms	Cycloprop[2,3]indeno[5,6-b]furan-2(4H)-one, 5a,6,6a,6b,7,7a-hexahydro-7,7a-dihydroxy-3,5,6b-trimethyl-, (5aS,6aR,6bS,7S,7aR)- (5aS,6aR,6bS,7S,7aR)-7,7a-Dihydroxy-3,5,6b-trimethyl-5a,6,6a,6b,7,7a-hexahydrocyclopropa[2,3]indeno[5,6-b]furan-2(4H)-one

Description	8β,9α-Dihydroxylindan-4(5),7(11)-dien-8alpha,12-olide (compound 3), a sesquiterpene, has anti-LIMK1 activity. 8β,9α-Dihydroxylindan-4(5),7(11)-dien-8alpha,12-olide has inhibitory property on cell motility[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> LIM Kinase (LIMK)
Target	LIMK1
References	[1]. Jianjiang Fu, et al. In vitro inhibitory properties of sesquiterpenes from Chloranthus serratus on cell motility via down-regulation of LIMK1 activation in human breast cancer. Phytomedicine. 2018 Oct 1;49:23-31.