70421-30-6

70421-30-6 structure

Name: 1-β-D-Ribofuranosyl-1H-pyrazolo[3,4-d]pyrimidine-4,6-diamine
Chemical Name: 1-(β-D-Ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine-4,6-diamine
CAS Number: 70421-30-6
Molecular Formula: C₁₀H₁₄N₆O₄
Molecular Weight: 282.26
Catalog: Signaling Pathways Cell Cycle/DNA Damage Nucleoside Antimetabolite/Analog
Create Date: 2018-07-01 12:32:14
Modify Date: 2024-02-05 18:15:39
1-β-D-Ribofuranosyl-1H-pyrazolo[3,4-d]pyrimidine-4,6-diamine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Name	1-(β-D-Ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine-4,6-diamine
Synonyms	1H-Pyrazolo[3,4-d]pyrimidine-4,6-diamine, 1-β-D-ribofuranosyl- 1-(β-D-Ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine-4,6-diamine

Description	1-β-D-Ribofuranosyl-1H-pyrazolo[3,4-d]pyrimidine-4,6-diamine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog
References	[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.