1334177-95-5
1334177-95-5 structure
- Name: NHS-PEG4-SPDP
- Chemical Name: N-{15-[(2,5-Dioxo-1-pyrrolidinyl)oxy]-15-oxo-3,6,9,12-tetraoxapentadec-1-yl}-3-(2-pyridinyldisulfanyl)propanamide
- CAS Number: 1334177-95-5
- Molecular Formula: C23H33N3O9S2
- Molecular Weight: 559.653
- Catalog: Signaling Pathways PROTAC PROTAC Linker
- Create Date: 2018-06-30 14:33:43
- Modify Date: 2024-01-10 07:12:56
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SPDP-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
| Name | N-{15-[(2,5-Dioxo-1-pyrrolidinyl)oxy]-15-oxo-3,6,9,12-tetraoxapentadec-1-yl}-3-(2-pyridinyldisulfanyl)propanamide |
|---|---|
| Synonyms |
N-{15-[(2,5-Dioxo-1-pyrrolidinyl)oxy]-15-oxo-3,6,9,12-tetraoxapentadec-1-yl}-3-(2-pyridinyldisulfanyl)propanamide
Propanamide, N-[15-[(2,5-dioxo-1-pyrrolidinyl)oxy]-15-oxo-3,6,9,12-tetraoxapentadec-1-yl]-3-(2-pyridinyldithio)- |
| Description | SPDP-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
|---|---|
| Related Catalog | |
| Target |
PEGs Alkyl/ether |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| References |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Molecular Formula | C23H33N3O9S2 |
| Molecular Weight | 559.653 |
| Exact Mass | 559.165833 |
| LogP | -0.89 |
| Index of Refraction | 1.579 |
| Storage condition | -20°C |