1353853-39-0

1353853-39-0 structure

Name: Fmoc-Phe-OH-d8
Chemical Name: N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-(α,β,β,2,3,4,5,6-2H8)phenylalanine
CAS Number: 1353853-39-0
Molecular Formula: C₂₄H₁₃D₈NO₄
Molecular Weight: 395.48
Create Date: 2018-07-02 14:34:53
Modify Date: 2024-01-20 16:29:24
Fmoc-Phe-OH-d8 is the deuterium labeled Fmoc-Phe-OH.

Name	N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-(α,β,β,2,3,4,5,6-2H8)phenylalanine
Synonyms	L-Phenylalanine-α,β,β,2,3,4,5,6-d8, N-[(9H-fluoren-9-ylmethoxy)carbonyl]- N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-(α,β,β,2,3,4,5,6-2H8)phenylalanine

Description	Fmoc-Phe-OH-d8 is the deuterium labeled Fmoc-Phe-OH.
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.