168828-60-2
168828-60-2 structure
- Name: PNU-101603
- Chemical Name: N-({(5S)-3-[3-Fluoro-4-(1-oxido-4-thiomorpholinyl)phenyl]-2-oxo-1,3-oxazolidin-5-yl}methyl)acetamide
- CAS Number: 168828-60-2
- Molecular Formula: C16H20FN3O4S
- Molecular Weight: 369.411
- Catalog: Signaling Pathways Anti-infection Bacterial
- Create Date: 2018-07-03 09:32:00
- Modify Date: 2024-01-10 09:51:15
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PNU-101603 is a metabolite of Sutezolid (HY-10392). PNU-101603 has excellent activity against Mycobacterium tuberculosis (MTB)[1].
| Name | N-({(5S)-3-[3-Fluoro-4-(1-oxido-4-thiomorpholinyl)phenyl]-2-oxo-1,3-oxazolidin-5-yl}methyl)acetamide |
|---|---|
| Synonyms |
N-({(5S)-3-[3-Fluoro-4-(1-oxido-4-thiomorpholinyl)phenyl]-2-oxo-1,3-oxazolidin-5-yl}methyl)acetamide
Acetamide, N-[[(5S)-3-[3-fluoro-4-(1-oxido-4-thiomorpholinyl)phenyl]-2-oxo-5-oxazolidinyl]methyl]- N-({(5S)-3-[3-fluoro-4-(1-oxidothiomorpholin-4-yl)phenyl]-2-oxo-1,3-oxazolidin-5-yl}methyl)acetamide |
| Description | PNU-101603 is a metabolite of Sutezolid (HY-10392). PNU-101603 has excellent activity against Mycobacterium tuberculosis (MTB)[1]. |
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| Related Catalog | |
| In Vitro | PNU-101603 (compound 7, 21 days) inhibits M. tuberculosis activity[2]. Cell Viability Assay[2] Cell Line: M. tuberculosis Concentration: 0-1 μg/mL approximately Incubation Time: 21 days Result: Inhibited M. tuberculosis with a MIC value ≤0.125 μg/mL. |
| Density | 1.5±0.1 g/cm3 |
|---|---|
| Boiling Point | 698.8±55.0 °C at 760 mmHg |
| Molecular Formula | C16H20FN3O4S |
| Molecular Weight | 369.411 |
| Flash Point | 376.4±31.5 °C |
| Exact Mass | 369.115845 |
| LogP | -1.20 |
| Vapour Pressure | 0.0±2.2 mmHg at 25°C |
| Index of Refraction | 1.645 |