37731-67-2

37731-67-2 structure

Name: 3’-Deoxy-3’-α-C-methyl-5-fluorouridine
Chemical Name: 3'-Deoxy-5-fluoro-3'-methyluridine
CAS Number: 37731-67-2
Molecular Formula: C₁₀H₁₃FN₂O₅
Molecular Weight: 260.22
Catalog: Signaling Pathways Cell Cycle/DNA Damage Nucleoside Antimetabolite/Analog
Create Date: 2018-06-02 06:52:49
Modify Date: 2024-01-02 16:48:30
3’-Deoxy-3’-α-C-methyl-5-fluorouridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Name	3'-Deoxy-5-fluoro-3'-methyluridine
Synonyms	Uridine, 3'-deoxy-5-fluoro-3'-methyl- 3'-Deoxy-5-fluoro-3'-methyluridine

Description	3’-Deoxy-3’-α-C-methyl-5-fluorouridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog	Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog Research Areas >> Others
References	[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.