518044-42-3
518044-42-3 structure
- Name: Mal-PEG6-acid
- Chemical Name: 1-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)-3,6,9,12,15,18-hexaoxahenicosan-21-oic acid
- CAS Number: 518044-42-3
- Molecular Formula: C19H31NO10
- Molecular Weight: 433.450
- Catalog: Signaling Pathways PROTAC PROTAC Linker
- Create Date: 2018-06-20 02:35:09
- Modify Date: 2024-09-05 22:02:25
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Mal-PEG6-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
| Name | 1-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)-3,6,9,12,15,18-hexaoxahenicosan-21-oic acid |
|---|---|
| Synonyms |
3,6,9,12,15,18-Hexaoxaheneicosan-21-oic acid, 1-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-
1-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)-3,6,9,12,15,18-hexaoxahenicosan-21-oic acid |
| Description | Mal-PEG6-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. |
|---|---|
| Related Catalog | |
| Target |
PEGs |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. |
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Boiling Point | 578.2±50.0 °C at 760 mmHg |
| Molecular Formula | C19H31NO10 |
| Molecular Weight | 433.450 |
| Flash Point | 303.5±30.1 °C |
| Exact Mass | 433.194794 |
| LogP | -2.16 |
| Vapour Pressure | 0.0±3.5 mmHg at 25°C |
| Index of Refraction | 1.501 |