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113318-05-1

113318-05-1 structure
113318-05-1 structure
  • Name: THYMOSIN BETA4 (16-38)
  • Chemical Name: (4S,7S,10S,13S,16S,19S)-4-[{[(1S)-5-Amino-1-carboxypentyl]imino}(hydroxy)methyl]-19-{[(2S)-6-amino-2-{[(2S)-2-({[(2S)-1-(N-{[(2S)-1-{N-[(2S,5S,8S,11S,14S,17S,20S,23S,26S,29S)-29,33-diamino-2,20,23-tris(4-aminobutyl)-5,14-bis(2-carboxyethyl)-1,4,7,10,13,16,19,22,25,28-decahydroxy-11,17-bis[(1R)-1-hydroxyethyl]-8-(3-hydroxy-3-iminopropyl)-26-isobutyl-3,6,9,12,15,18,21,24,27-nonaazatritriaconta-3,6,9,12,15,18,21,24,27-nonaen-1-ylidene]-4-imino-L-homoseryl}-2-pyrrolidinyl](hydroxy)methylene}-L-leucyl)-2-pyrrolidinyl](hydroxy)methylene}amino)-1,3-dihydroxypropylidene]amino}-1-hydroxyhexylidene]amino}-13-[(2S)-2-butanyl]-10-(2-carboxyethyl)-6,9,12,15,18-pentahydroxy-16-[(1R)-1-hydroxyethyl]-7-(3-hydroxy-3-iminopropyl)-5,8,11,14,17-pentaazadocosa-5,8,11,14,17-pentaene-1,22-dioic acid
  • CAS Number: 113318-05-1
  • Molecular Formula: C118H204N32O41
  • Molecular Weight: 2727.072
  • Catalog: Signaling Pathways Cytoskeleton Myosin
  • Create Date: 2018-06-07 05:07:48
  • Modify Date: 2024-01-14 13:02:51
  • 16-38-Thymosin β4 (cattle) is a Ca2+-independent MLCK activator with high affinity.

Name (4S,7S,10S,13S,16S,19S)-4-[{[(1S)-5-Amino-1-carboxypentyl]imino}(hydroxy)methyl]-19-{[(2S)-6-amino-2-{[(2S)-2-({[(2S)-1-(N-{[(2S)-1-{N-[(2S,5S,8S,11S,14S,17S,20S,23S,26S,29S)-29,33-diamino-2,20,23-tris(4-aminobutyl)-5,14-bis(2-carboxyethyl)-1,4,7,10,13,16,19,22,25,28-decahydroxy-11,17-bis[(1R)-1-hydroxyethyl]-8-(3-hydroxy-3-iminopropyl)-26-isobutyl-3,6,9,12,15,18,21,24,27-nonaazatritriaconta-3,6,9,12,15,18,21,24,27-nonaen-1-ylidene]-4-imino-L-homoseryl}-2-pyrrolidinyl](hydroxy)methylene}-L-leucyl)-2-pyrrolidinyl](hydroxy)methylene}amino)-1,3-dihydroxypropylidene]amino}-1-hydroxyhexylidene]amino}-13-[(2S)-2-butanyl]-10-(2-carboxyethyl)-6,9,12,15,18-pentahydroxy-16-[(1R)-1-hydroxyethyl]-7-(3-hydroxy-3-iminopropyl)-5,8,11,14,17-pentaazadocosa-5,8,11,14,17-pentaene-1,22-dioic acid
Description 16-38-Thymosin β4 (cattle) is a Ca2+-independent MLCK activator with high affinity.
Related Catalog
Target

MLCK[1].

In Vitro 16-38-Thymosin β4 cattle (50 pM) 在没有外源性钙调素 (CaM) 的情况下,显著增加 LC2 的磷酸化百分比。
References

[1]. Galoyan AA, et al. A hypothalamic activator of calmodulin-dependent enzymes is thymosin beta 4 (1-39). Neurochem Res. 1992 Aug;17(8):773-7.  

Density 1.5±0.1 g/cm3
Boiling Point 2127.1±75.0 °C at 760 mmHg
Molecular Formula C118H204N32O41
Molecular Weight 2727.072
Flash Point 1240.2±37.1 °C
Exact Mass 2725.486084
LogP 8.38
Vapour Pressure 0.0±0.6 mmHg at 25°C
Index of Refraction 1.649