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1189112-05-7

1189112-05-7 structure
1189112-05-7 structure
  • Name: HO-PEG14-OH
  • Chemical Name: PEG14
  • CAS Number: 1189112-05-7
  • Molecular Formula: C28H58O15
  • Molecular Weight: 634.751
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2018-06-25 17:04:29
  • Modify Date: 2024-01-02 19:45:02
  • HO-PEG14-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name PEG14
Synonyms PEG14
3,6,9,12,15,18,21,24,27,30,33,36,39-Tridecaoxahentetracontane-1,41-diol
MFCD09910394
Description HO-PEG14-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Density 1.1±0.1 g/cm3
Boiling Point 660.2±50.0 °C at 760 mmHg
Molecular Formula C28H58O15
Molecular Weight 634.751
Flash Point 353.1±30.1 °C
Exact Mass 634.377563
LogP -5.81
Vapour Pressure 0.0±4.5 mmHg at 25°C
Index of Refraction 1.466
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