1329835-60-0

1329835-60-0 structure

Name: Mexiletine D6 hydrochloride
Chemical Name: 1-(2,6-Dimethylphenoxy)-2-(2H6)propanamine hydrochloride (1:1)
CAS Number: 1329835-60-0
Molecular Formula: C₁₁H₁₂D₆ClNO
Molecular Weight: 221.757
Catalog: Signaling Pathways Membrane Transporter/Ion Channel Sodium Channel
Create Date: 2018-06-07 16:37:04
Modify Date: 2024-01-04 12:45:36
Mexiletine D6 hydrochloride (KOE-1173 D6 hydrochloride) is a deuterium labeled Mexiletine hydrochloride (KOE-1173 hydrochloride). Mexiletine hydrochloride, a Class IB antianhythmic, is a non-selective voltage-gated sodium channel blocker[1].

Name	1-(2,6-Dimethylphenoxy)-2-(2H6)propanamine hydrochloride (1:1)
Synonyms	2-Propan-1,1,2,3,3,3-d6-amine, 1-(2,6-dimethylphenoxy)-, hydrochloride (1:1) 1-(2,6-Dimethylphenoxy)-2-(2H6)propanamine hydrochloride (1:1)

Description	Mexiletine D6 hydrochloride (KOE-1173 D6 hydrochloride) is a deuterium labeled Mexiletine hydrochloride (KOE-1173 hydrochloride). Mexiletine hydrochloride, a Class IB antianhythmic, is a non-selective voltage-gated sodium channel blocker[1].
Related Catalog	Signaling Pathways >> Membrane Transporter/Ion Channel >> Sodium Channel Research Areas >> Cardiovascular Disease
References	[1]. Mori K, et al. Inhibitory effects of class I and IV antiarrhythmic drugs on the Na+-activated K+ channel current in guinea pig ventricular cells. Naunyn Schmiedebergs Arch Pharmacol. 1998 Dec;358(6):641-8.